Juarranz 1998.

Study characteristics
Methods	Design: Randomized controlled trial Setting: Primary care centre, Spain Recruitment: By telephone from healthcare centre lists
Participants	195 adults who smoked (aged 16 ‐ 65), 48% female, av.age 37, 23 cpd
Interventions	Intervention: participants received the following from their doctor and nurse: ‐ Brief standardized advice (3 ‐ 5 minutes) about smoking cessation ‐ An instruction booklet ‐ Nicotine patches ‐ A follow‐up phone call 2 days after the quit date ‐ Additional visits at 2 weeks, 3 months and 6 months Control: participants received usual care. No further details reported
Outcomes	Continuous abstinence at 6m Validation: Expired CO < 8 ppm
Funding Source	Not reported
Author's declarations of interest	Not reported
Notes	Strategy: Adjunctive counseling + cost‐free medications Level: Patient Comparison type: Multicomponent vs. standard care
Risk of bias
Bias	Authors' judgement	Support for judgement
Sequence Generation	High risk	Potential participants were ranked randomly in a list, then assigned alternately from list
Allocation concealment	High risk	Assigned from open list
Blinding of outcome assessors All outcomes	Low risk	Smoking status was validated by carbon monoxide
Incomplete outcome data All outcomes	Low risk	The overall loss to follow‐up was 4.9% (n = 10/205); 5.9% (n=6/102) in the intervention group and 3.9% (n = 4/103) in the control group were lost to follow‐up at 6 months.