Lasser 2017.

Study characteristics
Methods	Design: Randomized controlled trial Setting: Boston Medical Center’s adult primary care, USA Recruitment: Calls and letters to potentially eligible identified from electronic medical record, and recruited from waiting rooms
Participants	352 participants, av.age 50, 54% F, 15 cpd
Interventions	Intervention: participants received a low literacy smoking cessation brochure and a list of hospital and community resources for smoking cessation. In addition, they received up to 4 hours of patient navigation delivered over 6 months, and financial incentives for biochemically‐confirmed smoking cessation at 6 and 12 months following enrolment Control: participants received assessment of their smoking status, brief cessation counseling, a low‐literacy smoking cessation brochure and a list of hospital and community resources for smoking cessation
Outcomes	7‐day PPA at 12m Validation: Salivary cotinine > 10 ng/mL or urinary anabasine > 3 ng/mL
Funding Source	This study was supported by American Cancer Society (grant No. 125785‐RSG‐14‐034‐01CPPB)
Author's declarations of interest	QUOTE: "Dr Quintiliani was a consultant on a research grant to Partners HealthCare Inc. unrelated to the work presented in this article. No other conflicts are reported"
Notes	Strategy: Adjunctive counseling + Financial incentive Level: Patient Comparison type: Multicomponent vs. standard care
Risk of bias
Bias	Authors' judgement	Support for judgement
Sequence Generation	Low risk	Random‐number generator
Allocation concealment	Low risk	Sealed envelopes
Blinding of outcome assessors All outcomes	Low risk	Smoking status biochemically validated
Incomplete outcome data All outcomes	Low risk	The overall loss to follow‐up was 28.7% (n = 101/352); 27.1% (n = 48/177) in the intervention group and 30.3% (n = 53/175) in the control group were lost to follow‐up at 12 months