NCT04236687.

Study name	PAE compared to Holmium laser enucleation of the prostate for BPH
Methods	Study design: parallel randomized controlled trial (open label) Setting/Country: single center / Spain
Participants	Inclusion criteria Patients evaluated in the urology department and candidates to surgical treatment Age > 45 years IPSS ≥ 10 Qmax < 12 mL/s PVR < 300 mL Prostatic volume between 20 mL and 250 mL assessed by ultrasound Signed informed consent
Interventions	Group A: PAE Group B: Holmium laser enucleation of the prostate
Outcomes	Primary outcome Improvement of symptoms assessed by IPSS Secondary outcomes Qmax PVR PSA Procedure related adverse events assessed by Clavien‐Dindo modified score Procedure related effects on sexual function assessed by IIEF Procedure related effects on urinary continence assessed by the International Consultation on Continence Questionnaire Short Form
Starting date	February 2020
Contact information	fagreda.germanstrias@gencat.cat
Notes	Sponsor: Hospital Universitari Germans Trias i Pujol