| 2.1 RM vs UC: exacerbations: number of people experiencing 1 or more exacerbations |
4 |
424 |
Odds Ratio (M‐H, Random, 95% CI) |
1.02 [0.67, 1.55] |
| 2.1.1 3 to < 6 months |
1 |
45 |
Odds Ratio (M‐H, Random, 95% CI) |
1.58 [0.33, 7.59] |
| 2.1.2 6 to < 12 months |
2 |
210 |
Odds Ratio (M‐H, Random, 95% CI) |
0.81 [0.34, 1.93] |
| 2.1.3 ≥ 12 months |
1 |
169 |
Odds Ratio (M‐H, Random, 95% CI) |
1.17 [0.64, 2.14] |
| 2.2 RM vs UC: exacerbations: mean number of exacerbations (subgroup duration) |
2 |
297 |
Std. Mean Difference (IV, Random, 95% CI) |
0.22 [‐0.01, 0.44] |
| 2.2.1 6 to < 12 months |
1 |
68 |
Std. Mean Difference (IV, Random, 95% CI) |
0.33 [‐0.15, 0.81] |
| 2.2.2 ≥ 12 months |
1 |
229 |
Std. Mean Difference (IV, Random, 95% CI) |
0.18 [‐0.08, 0.44] |
| 2.3 RM vs UC: time to first exacerbation |
1 |
|
Hazard Ratio (IV, Random, 95% CI) |
Totals not selected |
| 2.4 RM vs UC: quality of life: SGRQ total (duration of treatment) |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 2.4.1 3 to < 6 months |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 2.5 RM vs UC: quality of life: CAT total score |
3 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 2.5.1 6 to < 12 months |
2 |
405 |
Mean Difference (IV, Random, 95% CI) |
0.06 [‐1.34, 1.45] |
| 2.5.2 ≥ 12 months |
1 |
229 |
Mean Difference (IV, Random, 95% CI) |
0.10 [‐1.42, 1.62] |
| 2.6 RM vs UC: dyspnoea symptoms: CRQ‐SAS |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 2.7 RM vs UC: hospital service utilisation: number of people admitted to hospital |
2 |
357 |
Odds Ratio (M‐H, Random, 95% CI) |
1.21 [0.75, 1.94] |
| 2.7.1 3 to < 6 months |
1 |
45 |
Odds Ratio (M‐H, Random, 95% CI) |
1.58 [0.33, 7.59] |
| 2.7.2 6 to < 12 months |
1 |
312 |
Odds Ratio (M‐H, Random, 95% CI) |
1.18 [0.72, 1.94] |
| 2.8 RM vs UC: hospital service utilisation: mean hospital admissions (all‐cause) (single) |
4 |
1409 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.02 [‐0.22, 0.19] |
| 2.9 RM vs UC: hospital service utilisation: hospital admissions (COPD‐related) |
2 |
129 |
Mean Difference (IV, Random, 95% CI) |
‐0.19 [‐0.41, 0.02] |
| 2.10 RM + fb vs RM: hospital service utilisation: HR: time to first hospitalisation after start of intervention |
1 |
|
Hazard Ratio (IV, Random, 95% CI) |
Totals not selected |
| 2.11 RM vs UC: hospital service utilisation: length of stay (all‐cause) |
5 |
1638 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.05 [‐0.19, 0.08] |
| 2.12 RM vs UC: hospital service utilisation: length of stay (COPD‐related) |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Totals not selected |
| 2.13 RM vs UC: mortality (all‐cause) |
6 |
798 |
Odds Ratio (M‐H, Random, 95% CI) |
0.68 [0.37, 1.25] |
