Chatwin 2016.
Methods |
Study design: multi‐centre, single‐blinded, stratified randomised controlled trial in United Kingdom Duration: 52 weeks Setting: primary and secondary clinics |
Participants |
Population: 68 adults recruited from outpatient and inpatient clinics at Royal Brompton & Harefield NHS Foundation Trust, West Middlesex University Hospital, and St George’s University Hospital Baseline characteristics: % Male: 63 all, Mean age: 65.3 all, % White: not reported, % African: not reported, % LTOT: 59 all, % Home oxygen: not reported, % Anxiety and depression 8 (4) all and 7 (4) all, Baseline medications: not reported, FEV₁: all 0.9 (0.5), FVC: all 2.1 (0.9), FEV₁/FVC: not reported, Current smokers (n): not reported, GOLD stage: all 3 (1), COPD exacerbations last 12 months: not reported, Hospitalisations in past 12 months: not reported Inclusion criteria: ≥ 18 years old, COPD or chronic respiratory failure due to another chronic respiratory disease, admitted exacerbation in previous 6 months, met criteria for LTOT or had oxygen saturation level ≤ 90% on air for past admission Exclusion criteria: cognitive impairment that impairs understanding of the trial or use of telemonitoring, age < 18 years |
Interventions | Measurements taken at baseline and at 3, 6, and 12 months Treatment arms
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Outcomes |
Primary outcomes: time to first hospital admission for exacerbation Secondary outcomes: hospital admissions, general practitioner (GP) consultations and home visits by nurses, quality of life measured by EuroQoL‐5D and hospital anxiety and depression (HAD) scale, self‐efficacy score |
Notes |
Funding: National Institute for Health Research (NIHR) under the Collaborations for Leadership in Applied Health Research and Care (CLAHRC) programme for North West London Other identifier:NCT02180919 |