Irct2016111016123N.

Study name	Effect of vitamin D and calcium supplementation on serum levels of hormones affecting postpartum depression
Methods	Randomised controlled double‐blind trial
Participants	Body mass index (BMI) less than 35; age 18 to 45 years; earning a score of 12 and above in Edinburgh questionnaire; time period ranging from 1 month until 6 months after childbirth Exclusion criteria: normal or above normal range for vitamin D levels; chronic diseases such as diabetes; renal failure; gastrointestinal diseases; liver problems; thyroid problems; kidney stones; cancer in the past 5 years; birth abnormalities; taking contraceptive drugs; endocrine disorders; severe depression and other mental disorders; using antidepressants
Interventions	Intervention 1: 50,000 IU pearl vitamin D3, every 14 days + 500 milligram calcium carbonate tablet, daily, for 8 weeks Intervention 2: 50,000 IU pearl vitamin D3, every 14 days + calcium carbonate placebo, daily, for 8 weeks Intervention 3: pearl paraffin as vitamin D placebo, every 14 days + calcium carbonate placebo, daily, for 8 weeks
Outcomes	Cortisol (time point: before and after 8 weeks of intervention). Method of measurement: serum level SECONDARY OUTCOMES: blood pressure, body mass index, depression severity, serum calcium (time point: before the intervention, end of the fourth week and end of the eighth week)
Starting date	28/08/2017
Contact information	Sima Jafarirad, Ahvaz Jundishapur University of Medical Science, Golestan Blv. Ahvaz, Iran. sjafarirad@gmail.com
Notes	http://en.irct.ir/trial/15190