Table 2.
Comparison of demographic data and clinical characteristics between POAG, NTG, and PACG patients
| Demographic characteristic | POAG (N = 60) | NTG (N = 52) | PACG (N = 52) | p value |
|---|---|---|---|---|
| Mean age (at first diagnosis) (mean, SD) | 63.0 (9.4) | 59.6 (10.3) | 62.3 (8.5) | 0.148@ |
| Mean age (at recruitment) (mean, SD) | 68.2 (9.4) | 65.6 (8.8) | 66.2 (8.7) | 0.269@ |
| Duration of follow-up (mean, SD) | 5.4 (4.4) | 6.2 (4.4) | 4.2 (3.3) | 0.037 @ |
| Sex (n, %) | ||||
| Male | 43 (71.7) | 30 (57.7) | 19 (36.5) | 0.001 # |
| Female | 17 (28.3) | 22 (42.3) | 33 (63.5) | |
| Ethnicity (n, %) | ||||
| Malay | 30 (50.0) | 32 (61.6) | 33 (63.5) | 0.597* |
| Chinese | 28 (46.7) | 18 (34.6) | 17 (32.7) | |
| Indian | 2 (3.3) | 2 (3.8) | 2 (3.8) | |
| Type of glaucoma (n, %) | 60 (36.6) | 52 (31.7) | 52 (31.7) | |
| Central cornea thickness, μm (mean, SD) | 527.6 (28.1) | 515.6 (31.0) | 512.8 (40.7) | 0.118@ |
| Systemic disease | ||||
| Hypertension (n, %) | 44 (73.3) | 38 (73.1) | 29 (55.8) | 0.085 # |
| Diabetes mellitus (n, %) | 27 (45.0) | 10 (19.2) | 15 (28.8) | 0.012 # |
| Ischemic heart disease (n, %) | 14 (23.3) | 8 (15.4) | 6 (11.5) | 0.236# |
| Hyperlipedemia (n, %) | 22 (36.7) | 23 (44.2) | 18 (34.6) | 0.566# |
| BMI (mean, SD) | 23.1 (3.5) | 24.8 (5.5) | 25.8 (4.0) | 0.004 @ |
| Waist circumference (mean, SD) | 89.6 (11.1) | 94.6 (11.2) | 95.6 (10.2) | 0.008 @ |
| Neck circumference (mean, SD) | 37.4 (8.3) | 35.9 (4.1) | 36.4 (6.0) | 0.454@ |
| APAC (n, %) | ||||
| No | – | – | 35 (67.3) | – |
| Yes | – | – | 17 (32.7) | |
| AGIS score (n, %) | ||||
| Early | 12 (20.0) | 7 (13.9) | 8 (15.4) | 0.828* |
| Mild | 23 (38.3) | 24 (46.1) | 18 (34.6) | |
| Moderate | 16 (26.7) | 15 (28.7) | 15 (28.8) | |
| Severe | 7 (11.7) | 5 (9.5) | 7 (13.5) | |
| End-stage | 2 (3.3) | 1 (1.8) | 4 (7.7) | |
BMI, body mass index; APAC, acute presentation of angle-closure; AGIS, advanced glaucoma intervention study
p < 0.05 is considered statistical significance based on Pearson's Chi-square
p < 0.05 is considered statistical significance based on Fisher's exact test
p < 0.05 is considered statistical significance based on one-way ANOVA