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. Author manuscript; available in PMC: 2021 Oct 25.
Published in final edited form as: Eur Respir J. 2021 Oct 14;58(4):2004149. doi: 10.1183/13993003.04149-2020

Figure 6. Exposure to healthy control but not ARDS BALF increases complement gene and protein but not coagulation cascade gene expression.

Figure 6.

Figure 6.

Complement genes (A) expressed by ARDS-exposed (n=5) and healthy control BALF (n=5) samples were compared to PBS-exposed hMSCs (n=4). Levels of complement secreted into the conditioned media by HC or ARDS BALF compared to PBS-exposed hMSCs are depicted in B-C. Two different hMSC donors were used. Abbreviations: HC, healthy control; ARDS, acute respiratory distress syndrome; PBS, phosphate-buffered saline; TFP1, tissue factor. Coagulation cascade genes (D) expressed by ARDS-exposed (n=5) and healthy control BALF (n=5) samples were compared to PBS-exposed hMSCs (n=4). Gene expression data are presented as mean of log2 fold change. Complement (C3a) levels are depicted media with interquartile range.