Table 5.
The top 20 genes relevant genes with breast cancer derived from the 985 pathogenetic transcripts and the 1970 transcripts
| 985 transcripts | 1970 transcripts | ||
|---|---|---|---|
| Germline | Cancer | Germline | Cancer |
| TCF3 | GATA3 | FOXP1 | CASP8 |
| FOXP1 | APC | TCF3 | PALB2 |
| LEF1 | RNF213 | SPATA31A3 | RXFP3 |
| PAFAH1B2 | PIK3CA | PAFAH1B2 | DOCK2 |
| BLM | PPP2R1A | CCNE1 | ANK1 |
| PPFIBP1 | CDH1 | ADAM23 | ADAM23 |
| PALB2 | CHD2 | NCOA4 | ITK |
| MUC4 | RUNX1 | KC6 | TCF3 |
| CCDC6 | MSH6 | PALB2 | CCNE1 |
| LIFR | CNBD1 | AMOT | FOXP1 |
| MITF | KMT2C | LEF1 | ABHD13 |
| CCNE1 | ARID1A | CPEB2 | SPATA31A3 |
| ZCCHC8 | TBX3 | SPATA31D1 | XPO6 |
| TP53 | KRAS | IL21 | FRYL |
| FOXO4 | CHD4 | BLM | RFC5 |
| EBF1 | KMT2D | ITK | SDHAF2 |
| TERT | NRAS | ZNF507 | POU4F1 |
| GMPS | MAP3K1 | CCDC6 | PICALM |
| CCNC | HLA-A | TERT | LEF1 |
The bold genes in the 985 transcripts are the ones found in COSMIC top 20 genes. The bold genes in the 1970 transcripts are the ones in the unknown transcripts