Table 3.

Cox model analysis of overall survival

Parameters	Relative risk (95% CI)	P-value
Univariate
Age	1.318(1.005–1.729)	0.046
Gender	0.740(0.557–0.983)	0.042
Smoking	1.009(0.767–1.327)	0.949
Alcohol	0.877(0.644–1.194)	0.405
Histological grade	0.828(0.643–1.067)	0.144
Stage	1.767(1.212–2.577)	0.003
T classification	1.386(1.114–1.723)	0.003
Lymph node metastasis	1.346(1.117–1.622)	0.002
Distant metastasis	1.050(0.818–1.348)	0.701
MKRN3 expression	1.004(1.002–1.006)	0.000
Multivariate
Lymph node metastasis	1.721(1.358–2.158)	0.000
T classification	1.916(1.389–2.643)	0.000
MKRN3 expression	1.004(1.002–1.006)	0.001

The bolditalic values represent P < 0.05

All the clinicopathological variables listed in the table were included in the univariate and multivariate analyses

95% CI, 95% confidence interval