Table 4.
Univariate Competing Risk Analysis of Predictors of Wait-list Removal Due to Improvement
| Predictor variables | Sub HR (95 % CI) | p |
|---|---|---|
| ALD (vs non-ALD) | ||
| At 6 months after listing* | 0.87 (0.74–1.03) | 0.11 |
| At 1 year after listing* | 1.22 (1.08–1.38) | < 0.001 |
| At 2 years after listing* | 2.39 (1.94–2.95) | < 0.001 |
|
| ||
| Age, yrs (vs 18–34) | ||
| 35–49 | 0.46 (0.39–0.55) | < 0.001 |
| 50–64 | 0.34 (0.29–0.41) | < 0.001 |
| 65 and older | 0.52 (0.42–0.64) | < 0.001 |
|
| ||
| Female Sex | 1.38 (1.25–1.53) | < 0.001 |
|
| ||
| Race (vs White) | ||
| Black | 1.12 (0.96–1.38) | 0.12 |
| Other | 0.91 (0.79–1.04) | 0.20 |
|
| ||
| BMI (vs 20–29) | ||
| Less than 20 | 1.82 (1.44–2.30) | < 0.001 |
| 30–34 | 0.61 (0.53–0.70) | < 0.001 |
| 35–39 | 0.65 (0.53–0.78) | < 0.001 |
| > or = 40 | 0.62 (0.46–0.82) | 0.001 |
|
| ||
| Blood group (vs AB) | ||
| A | 1.38 (1.01–1.89) | 0.04 |
| B | 1.46 (1.05–2.05) | 0.03 |
| O | 1.35 (0.99–1.84) | 0.06 |
|
| ||
| Ascites (Absent) | ||
| Slight | 0.24 (0.22–0.27) | < 0.001 |
| Moderate or more | 0.07 (0.05–0.09) | < 0.001 |
|
| ||
| Spontaneous bacterial peritonitis | 0.59 (0.45–0.78) | < 0.001 |
|
| ||
| Encephalopathy (vs none) | ||
| Grade 1–2 | 0.22 (0.20–0.25) | < 0.001 |
| Grade 3–4 | 0.04 (0.03–0.07) | < 0.001 |
|
| ||
| TIPSS | 0.89 (0.73–1.08) | 0.24 |
|
| ||
| Portal vein thrombosis | 0.82 (0.61–1.10) | 0.19 |
|
| ||
| Diabetes | 0.66 (0.58–0.76) | < 0.001 |
|
| ||
| Prior malignancy | 1.10 (0.88–1.37) | 0.38 |
|
| ||
| MELD at listing (vs < 15) | ||
| 15–24 | 0.54 (0.48–0.61) | < 0.001 |
| 25–34 | 0.53 (0.44–0.64) | < 0.001 |
| ≥ 35 | 0.42 (0.31–0.56) | < 0.001 |
|
| ||
| Region for listing, by grouping of wait-time (vs low) | ||
| Moderate | 1.01 (0.90–1.15) | 0.79 |
| Long | 0.84 (0.73–0.96) | 0.01 |
|
| ||
| Cohort (vs 2002–2006) | ||
| 2007–2011 | 1.98 (1.70–2.29) | < 0.001 |
| 2012–2016 | 2.75 (2.38–3.17) | < 0.001 |
Significant interaction between alcoholic liver disease and time since listing was identified (p < 0.001). Therefore, subhazard ratios are reported at 6 months, 1 year, and 2 years after listing.