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. 2021 Oct 25;21(12):823–828. doi: 10.1038/s41577-021-00640-w

Table 1.

Oral polio vaccines

Oral polio vaccine Protection offered Characteristics
tOPV Serotypes 1, 2 and 3 Inexpensive, effective and offers long-lasting protection
bOPV Serotypes 1 and 3 Stronger immune response against types 1 and 3 compared with tOPV. No immunity against serotype 2
mOPVs Serotype 1 (mOPV type 1), serotype 2 (mOPV type 2) and serotype 3 (mOPV type 3) Generate best immune response to the targeted serotype
nOPV2 Serotype 2 Genetically stable and less likely to be associated with the emergence of cVDPV2 in low-immunity settings

bOPV, bivalent oral polio vaccine; cVDPV2, circulating vaccine-derived poliovirus type 2; mOPV, monovalent oral polio vaccine; nOPV2, novel oral polio vaccine type 2; tOPV, trivalent oral polio vaccine.