Table 1.
Oral polio vaccines
Oral polio vaccine | Protection offered | Characteristics |
---|---|---|
tOPV | Serotypes 1, 2 and 3 | Inexpensive, effective and offers long-lasting protection |
bOPV | Serotypes 1 and 3 | Stronger immune response against types 1 and 3 compared with tOPV. No immunity against serotype 2 |
mOPVs | Serotype 1 (mOPV type 1), serotype 2 (mOPV type 2) and serotype 3 (mOPV type 3) | Generate best immune response to the targeted serotype |
nOPV2 | Serotype 2 | Genetically stable and less likely to be associated with the emergence of cVDPV2 in low-immunity settings |
bOPV, bivalent oral polio vaccine; cVDPV2, circulating vaccine-derived poliovirus type 2; mOPV, monovalent oral polio vaccine; nOPV2, novel oral polio vaccine type 2; tOPV, trivalent oral polio vaccine.