Table 4.
Classification of Chemicals Analyzed by Two or More Alternative Tests.
| Representative Chemicals | Alternative Tests | ||||||
|---|---|---|---|---|---|---|---|
| BCOP (LLBO) | BCOP (OP-KIT) | EpiOcular | ICE | OI | OS | STE | |
| Total Number | 121 | 145 | 144 | 67 | 74 | 81 | 117 |
| Non Classified | 35 | 40 | 50 | 18 | 37 | 37 | 51 |
| Irritant Classified | 86 | 105 | 94 | 49 | 37 | 44 | 66 |
| True Negatives | 16 | 16 | 33 | 4 | 22 | 24 | 46 |
| True Positives | 80 | 95 | 92 | 46 | 34 | 44 | *53 |
| False Negatives | 6 | 10 | 2 | 3 | 3 | 0 | 13 |
| False Positives | *19 | *24 | 17 | 14 | 15 | 13 | 5 |
Table 4. Classification of chemicals analyzed by two or more alternative tests. BCOP = Bovine Corneal Opacity and Permeability; LLBO = Laser Light-Based Opacitometer; ICE = Isolated Chicken Eye; OI = Ocular Irritection, OS = OptiSafe, STE = Short Time Exposure.
*
= has one less FP for BCOP (LLBO) and BCOP (OP-KIT) and one less TP for STE due to differing in vivo classification of cetylpyridinium bromide. The in vivo classification of cetylpyridinium bromide for LLBO and OP-KIT was not classified (NC) and the classification for STE was category 1.