Table 1.
Functional Enrichment for the Seventeen Modules Identified in the Trauma Dataset
| Module | Size | Top Term (P ≤) | Hub Gene |
|---|---|---|---|
| 2 | 1235 | Factor: hdac2 (5E-48) vesicle-mediated transport (5E-28) | GNB2 |
| 4 | 625 | Factor: ETF (5E-13) Endomembrane system (3E-12) | SERPINB1 |
| 5 | 565 | Translation (1E-22) Mitochondrion (4E-18) | MRPL57 |
| 6 | 323 | Translation (4E-39) | RPL8 |
| 7 | 163 | Platelet activation (7E-15) | GUCY1B1 |
| 8 | 241 | Factor: GABP-alpha (1E-8) Response to stress (6E-6) | MCL1 |
| 13 | 121 | T cell activation (5E-16) | BCL11B |
| 14 | 215 | Factor: ETF (9E-10) Protein transport (1E-6) | MIER1 |
| 15 | 108 | Cell cycle (1E-49) | HMMR |
| 16 | 733 | Myeloid leukocyte activation (2E-29) | FLOT2 |
| 17 | 105 | Factor: BTEB3 (1E-4) Nuclear lumen (3E-10) | AKAP13 |
| 18 | 1774 | Factor: ZF5 (6E-41) Nucleus (1E-42) | SRSF11 |
| 19 | 85 | Erythrocyte differentiation (1E-7) | SELENBP1 |
| 20 | 85 | hsa-miR-576-3p (0.005) | ANAPC13 |
| 22 | 74 | Factor: IRF1 (6E-27) defense response to virus (7E-29) | IFI44L |
| 25 | 53 | Neutrophil degranulation (1E-4) | BASP1 |
| 27 | 33 | Neutrophil activation (3E-28) | CEACAM6 |
Notes: Hub gene is the top gene with high intra-module connectivity in each module. Size: the number of genes in a module. Module: the numerical label for each module. Top term: the informative and significant functional terms for each module.