Table 2. Comparison of the response to curative treatments in the elderly and young patients with hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (iCCA).
Treatment | Tumor | Findings | Ref. |
Liver resection | HCC | Comparable effectiveness and safety Longer hospitalization and rehabilitation |
[98–100] |
iCCA | Low mortality Severe complications when ≤45% remnant liver |
[101] | |
Liver transplant | HCC | Acceptable long-term survival Controversial results in high-risk patients |
[103, 104, 107] |
iCCA | Similar 5-year survival when tumor size ≤2 cm | [108] | |
Radiofrequency ablation | HCC | Comparable effectiveness and safety | [109, 110] |
iCCA | Comparable effectiveness in iCCA | [111] | |
Microwave ablation | HCC | Comparable effectiveness and safety in patients >65 | [112] |
iCCA | Good survival and safety in iCCA patients when tumor size ≤2 cm | [113] |