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. 2021 Oct 11;13(19):23416–23434. doi: 10.18632/aging.203620

Table 2. Comparison of the response to curative treatments in the elderly and young patients with hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (iCCA).

Treatment Tumor Findings Ref.
Liver resection HCC Comparable effectiveness and safety
Longer hospitalization and rehabilitation
[98100]
iCCA Low mortality
Severe complications when ≤45% remnant liver
[101]
Liver transplant HCC Acceptable long-term survival
Controversial results in high-risk patients
[103, 104, 107]
iCCA Similar 5-year survival when tumor size ≤2 cm [108]
Radiofrequency ablation HCC Comparable effectiveness and safety [109, 110]
iCCA Comparable effectiveness in iCCA [111]
Microwave ablation HCC Comparable effectiveness and safety in patients >65 [112]
iCCA Good survival and safety in iCCA patients when tumor size ≤2 cm [113]