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. 2021 Oct 4;13(19):22802–22829. doi: 10.18632/aging.203574

Table 4. Gene sets enriched in phenotype high.

MSigDB collection Gene set name NES NOM
p-value
FDR
q-value
c2.cp.kegg. v7.0.symbols. gmt [Curated] KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 2.177 0.000 0.000
KEGG_CELL_CYCLE 2.132 0.000 0.002
KEGG_OOCYTE_MEIOSIS 2.128 0.000 0.001
KEGG_PYRIMIDINE_METABOLISM 2.057 0.000 0.003
KEGG_NUCLEOTIDE_EXCISION_REPAIR 2.056 0.000 0.002
KEGG_SPLICEOSOME 1.981 0.002 0.004
KEGG_DNA_REPLICATION 1.968 0.000 0.004
KEGG_HOMOLOGOUS_RECOMBINATION 1.940 0.000 0.004
KEGG_MISMATCH_REPAIR 1.921 0.000 0.004
KEGG_P53_SIGNALING_PATHWAY 1.884 0.000 0.006

Abbreviations: NES: normalized enrichment score; NOM: nominal; FDR: false discovery rate. Gene sets with NOM p-value <0.05 and FDR q-value <0.05 are considered as significant.