Table 4. Gene sets enriched in phenotype high.
MSigDB collection | Gene set name | NES |
NOM
p-value |
FDR
q-value |
c2.cp.kegg. v7.0.symbols. gmt [Curated] | KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS | 2.177 | 0.000 | 0.000 |
KEGG_CELL_CYCLE | 2.132 | 0.000 | 0.002 | |
KEGG_OOCYTE_MEIOSIS | 2.128 | 0.000 | 0.001 | |
KEGG_PYRIMIDINE_METABOLISM | 2.057 | 0.000 | 0.003 | |
KEGG_NUCLEOTIDE_EXCISION_REPAIR | 2.056 | 0.000 | 0.002 | |
KEGG_SPLICEOSOME | 1.981 | 0.002 | 0.004 | |
KEGG_DNA_REPLICATION | 1.968 | 0.000 | 0.004 | |
KEGG_HOMOLOGOUS_RECOMBINATION | 1.940 | 0.000 | 0.004 | |
KEGG_MISMATCH_REPAIR | 1.921 | 0.000 | 0.004 | |
KEGG_P53_SIGNALING_PATHWAY | 1.884 | 0.000 | 0.006 |
Abbreviations: NES: normalized enrichment score; NOM: nominal; FDR: false discovery rate. Gene sets with NOM p-value <0.05 and FDR q-value <0.05 are considered as significant.