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This figure depicts the result of EC damage, loss of endothelial membrane and pathways, leading to irreversible PH. Cav-1 (caveolin-1), ECs (endothelial cells), EndMT (endothelial mesenchymal transition), PECAM-1 (Platelets’ endothelial cells’ adhesion molecules), PH (pulmonary hypertension), SMC (smooth muscle cells), VE-CAD (vascular endothelial cadherin).
