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. 2021 Oct 11;13:735524. doi: 10.3389/fnagi.2021.735524

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Copyright © 2021 Kotredes, Oblak, Pandey, Lin, Garceau, Williams, Uyar, O’Rourke, O’Rourke, Ingraham, Bednarczyk, Belanger, Cope, Foley, Logsdon, Mangravite, Sukoff Rizzo, Territo, Carter, Sasner, Lamb and Howell.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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KEGG pathways enrichment analysis. Significantly enriched KEGG pathways (p < 0.05) in the downregulated and upregulated list of genes across mouse models at different ages for both sexes. All alleles expressed were homozygous.