Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Oct 7;9:715883. doi: 10.3389/fcell.2021.715883

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Liu, Liu, Chen, Li, Wu, Tan, Zeng, Li, Zhou, Gao and Pei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The expression of HK2 in esophageal carcinoma (ESCA) and pan-carcinoma. (A) Oncomine analysis showed the expression level of HK2 mRNA in different tumor types. (B) The TIMER ESCA cohort shows that HK2 mRNA expression levels in different tumor types. (C) Differential expression of HK2 in ESCA and normal tissues was analyzed by TCGA ESCA cohort (D) Difference expression of HK2 in ESCA and normal tissues was analyzed by GSE38129 cohort. (E) Difference expression of HK2 between ESCA and matched normal tissues in GSE23400 cohort. (F) Difference expression of HK2 in different ESCA cell lines and human normal epithelial cell lines. Immunohistochemical staining showed the expression of HK2 in ESCA samples (G) and paracarcinoma samples (H). (I) The mean HK2 IHC score in ESCA tissue (2.32 ± 0.621) was significantly higher than that of matched peritumoral tissue (0.84 ± 0.618). ^∗P < 0.05; ^∗∗P < 0.01; ^∗∗∗P < 0.001; ^*⁣*⁣**P < 0.0001.