TABLE 1.
HK2 expression in cancerous vs. normal tissue in ONCOMINE.
| Cancer Site | Cancer type | P-value | t-test | Fold change | References (PMID) |
| Bladder | Infiltrating bladder urothelial carcinoma | 1.47E-12 | 8.112 | 3.119 | 16432078 |
| Superficial bladder cancer | 1.51E-16 | 10.627 | 4.207 | 16432078 | |
| Brain and CNS | Anaplastic oligoastrocytoma | 0.001 | 5.698 | 4.095 | 16357140 |
| Brain glioblastoma | 1.85E-8 | 14.506 | 5.631 | TCGA Brain | |
| Glioblastoma | 0.006 | 3.978 | 5.856 | TCGA Brain | |
| Glioblastoma | 8.11E-5 | 6.873 | 3.455 | 16204036 | |
| Oligodendroglioma | 1.50E-6 | 5.268 | 2.460 | 16616334 | |
| Anaplastic astrocytoma | 8.43E-5 | 4.200 | 2.491 | 16616334 | |
| Glioblastoma | 1.41E-4 | 7.815 | 2.820 | 18565887 | |
| Breast | Breast phyllodes tumor | 3.98E-4 | –6.710 | –2.365 | 22522925 |
| Colorectal | Cecum adenocarcinoma | 1.20E-6 | –6.579 | –2.080 | 17615082 |
| Rectal adenocarcinoma | 4.02E-17 | –9.720 | –2.146 | 20725992 | |
| Rectal mucinous adenocarcinoma | 1.33E-4 | –4.615 | –2.337 | TCGA Colorectal | |
| Colorectal carcinoma | 1.05E-5 | –5.676 | –2.198 | 20143136 | |
| Esophageal | Barrett’s esophagus | 0.003 | 2.929 | 3.157 | 16952561 |
| Esophageal adenocarcinoma | 9.76E-4 | 3.433 | 3.062 | 16952561 | |
| Gastric | Gastric mixed adenocarcinoma | 3.09E-5 | 5.339 | 2.638 | 19081245 |
| Head-Neck | Thyroid gland papillary carcinoma | 2.29E-4 | 4.668 | 2.487 | 17296934 |
| Kidney | Hereditary clear cell renal cell Carcinoma | 7.96E-29 | 30.305 | 13.568 | 19470766 |
| Non-hereditary clear cell renal cell Carcinoma | 4.45E-18 | 16.554 | 8.081 | 19470766 | |
| Clear cell renal cell carcinoma | 1.19E-7 | 10.778 | 14.045 | 17699851 | |
| Clear cell renal cell carcinoma | 5.80E-10 | 9.709 | 4.871 | 16115910 | |
| Leukemia | Acute myeloid leukemia | 4.30E-5 | –5.734 | –3.633 | 14770183 |
| B-Cell acute lymphoblastic leukemia | 1.74E-10 | –15.717 | –7.694 | 17410184 | |
| Acute myeloid leukemia | 5.30E-7 | –7.117 | –2.898 | 17410184 | |
| T-Cell acute lymphoblastic leukemia | 1.94E-6 | –7.774 | –9.190 | 17410184 | |
| B-Cell acute lymphoblastic leukemia | 2.46E-30 | –13.938 | –2.545 | 20406941 | |
| Chronic Lymphocytic Leukemia | 2.19E-38 | –20.361 | –3.118 | 20406941 | |
| T-Cell acute lymphoblastic leukemia | 1.77E-25 | –12.090 | –2.282 | 20406941 | |
| B-Cell childhood acute lymphoblastic Leukemia | 1.07E-26 | –13.463 | –2.221 | 20406941 | |
| Lymphoma | Unspecified peripheral T-cell Lymphoma | 2.43E-10 | 7.895 | 2.280 | 17304354 |
| Cutaneous follicular lymphoma | 1.68E-4 | –4.963 | –2.329 | 12713594 | |
| Ovarian | Ovarian serous adenocarcinoma | 1.00E-4 | 5.492 | 9.472 | 19486012 |
| Pancreas | Pancreatic carcinoma | 9.31E-10 | 8.709 | 6.691 | 19732725 |
| Pancreatic ductal adenocarcinoma | 1.92E-11 | 7.825 | 3.038 | 19260470 | |
| Pancreatic adenocarcinoma | 0.005 | 3.955 | 8.921 | 12651607 | |
| Sarcoma | Synovial sarcoma | 2.43E-5 | 5.554 | 3.867 | 15994966 |
| Round cell liposarcoma | 1.07E-4 | 5.031 | 3.686 | 15994966 | |
| Pleomorphic liposarcoma | 5.83E-4 | 4.806 | 5.595 | 15994966 | |
| Leiomyosarcoma | 2.03E-10 | –11.795 | –5.138 | 20601955 | |
| Dedifferentiated liposarcoma | 3.12E-9 | –10.393 | –4.032 | 20601955 | |
| Myxofibrosarcoma | 1.35E-7 | –6.913 | –2.914 | 20601955 | |
| Myxoid/round cell liposarcoma | 1.53E-5 | –5.634 | –2.140 | 20601955 |