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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Dev Med Child Neurol. 2021 Mar 22;63(8):984–990. doi: 10.1111/dmcn.14866

Table 3:

Unstandardized path model results

Parent direct effects Estimate SE Estimate/SE p
Hypothalamic involvement→HRQoL −1.08 2.73 −0.39 0.69
Diabetes insipidus→HRQoL 0.70 3.83 0.18 0.86
EDS→HRQoL −4.48 4.80 −0.93 0.35
Executive function→HRQoL −0.83 0.15 −5.48 <0.001 a
Hypothalamic involvement→executive function −2.7 1.78 −1.52 0.13
Diabetes insipidus→executive function −5.2 2.5 −2.05 0.04 a
EDS→executive function 5.6 3.2 1.8 0.08
Patient direct effects
 Hypothalamic involvement→HRQoL −2.4 2.6 −0.94 0.35
 Diabetes insipidus→HRQoL −2.4 3.6 −0.67 0.51
 EDS→HRQoL −5.6 4.2 −1.32 0.19
 Executive function→HRQoL −0.18 0.20 −0.87 0.38
Parent indirect effects
 Hypothalamic involvement→executive function→HRQoL 2.23 1.5 1.5 0.13
Diabetes insipidus→executive function→HRQoL −4.3 2.2 −2.0 0.049 b
 EDS→executive function→HRQoL −4.6 2.9 −1.6 0.11
Patient indirect effects
 Hypothalamic involvement→executive function→HRQoL 0.47 0.63 0.75 0.45
 Diabetes insipidus→executive function→HRQoL −0.91 1.14 −0.80 0.43
 EDS→executive function→HRQoL −0.99 1.3 −0.73 0.46
Residual covariance
Parent HRQoL with patient HRQoL 71.9 35.6 2.02 0.043 b

Bold type indicates statistically significant results:

a

p<0.001

b

p<0.05. SE, standard error; HRQoL, health-related quality of life; EDS, excessive daytime sleepiness.