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Liver in PAH and metabolic syndrome.
| PAH | Metabolic syndrome90–93 | |
|---|---|---|
| Lipid metabolism | ||
| VLDL | ↑ 74 | ↑ |
| LDL | ↓ 71 or ↔67,74 | ↑↑ |
| TG | ↓ or ↔ | ↑↑ |
| HDL | ↓↓ 94 | ↓ |
| TG/HDL | ↑ 72 - 75 | ↑ |
| Hepatic insulin resistance | No evidence of ↑ | ↑ |
| Hepatic insulin extraction | ↑ 85 | ↓ |
| Hepatic fat content | No evidence of ↑ | ↑↑ |
PAH: pulmonary arterial hypertension; VLDL: very-low-density lipoprotein; LDL: low-density lipoprotein; TG: triglycerides; HDL: high-density lipoprotein; ↑: increased; ↓: decreased; ↔: unchanged or normal.
