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. 2021 Oct 11;12:738431. doi: 10.3389/fimmu.2021.738431

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Copyright © 2021 Ramos, Das, Harrison, Garcia, Gadad and Dhandayuthapani

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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M. genitalium (Mg) and M. pneumoniae (Mp) regulate gene targets of specific transcription factors. (A) Transcription factor heat map showing fold enrichment profiles. Quantification of transcription factors enrichment in the RNA-seq dataset by dot blots for each condition: (B) Mg up-regulated, (C) Mp up-regulated, (D) Mg down-regulated, and (E) Mp down-regulated. Dot blots measure fold enrichment of the pathways, and dot size represents total number of genes included in each category, and gradient color shows statistical significance [-log₁₀(P)].