Table 4.

Associations between VEGF and cortical thickness ROI analyzed in each Aβ stratum

	Aβ+ (n=215)				Aβ− (n=95)
ROI	β	SE	p-value	FDR-p-value	β	SE	p-value	FDR-p-value
Superior Temporal Gyrus	0.23	0.12	0.051	0.15	−0.35	0.15	0.028	0.062
Middle Temporal Gyrus	0.24	0.12	0.049	0.15	−0.23	0.15	0.13	0.17
Inferior Temporal Gyrus	0.20	0.12	0.098	0.22	−0.22	0.14	0.12	0.17
Fusiform Gyrus	0.23	0.12	0.051	0.15	−0.35	0.15	0.028	0.062
Entorhinal Cortex	0.46	0.34	0.18	0.29	−0.42	0.49	0.39	0.43
Superior Parietal Cortex	−0.09	0.10	0.39	0.44	−0.41	0.14	0.004	0.032*
Inferior Parietal Cortex	0.12	0.11	0.28	0.35	−0.34	0.14	0.021	0.062
Posterior Cingulate	0.13	0.10	0.19	0.29	−0.11	0.14	0.43	0.43
Precuneus	0.13	0.10	0.99	0.99	−0.20	0.12	0.10	0.17

Each relationship was evaluated using a linear mixed effects model. Fixed effects included VEGF, age, sex, years of education, and CSF t-tau, APOE4, and diagnosis. Site was modeled using random effects. FDR=False Discovery Rate. SE = Standard Error.

^*indicates p< 0.05 significance.