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ROC curve and calculation of the cutoff value. A Receiver-operator curve was performed and the cutoff value of the platelet count before the initiation of treatment optimally predicting the closure of PDA was calculated. A platelet count ≥181 × 109/L was concluded as the cutoff value with area under the curve (AUC, 0.617); the confidence interval (CI) was 0.483–0.685; sensitivity, 0.729; specificity, 0.508; and Youden index, 0.220.
