Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Degradation of NETs as a risk factor for severe coinfections and damage of the lung. In the case of a severe lung infection, e.g., with SARS-CoV-2, neutrophils are activated and release NETs. The host itself produces nucleases to eliminate and recycle NET products. Importantly, nuclease-mediated degradation of NETs may promote the growth of certain bacteria that use degraded NET products as an efficient source for NAD or adenosine.
