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Dimeric Cp is found in the nucleolus. (a) Cp colocalizes with nucleolin at 16 h posttransfection with the HBV expression plasmids EL43 (expressing only Cp and X proteins) and LJ144 (expressing Cp, X, and P). (b) The EL43-Y132A plasmid expresses assembly-deficient Cp that can only form dimers. Dimeric Cp colocalizes with nucleolar markers nucleolin, fibrillarin, and B23 (i.e., nucleophosmin).
