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. 2021 Feb 16;12(1):e03617-20. doi: 10.1128/mBio.03617-20

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Copyright © 2021 Roubidoux et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — Stalk specific MAbs have various degrees of breadth. The phylogenetic tree shows representative HA protein sequences for each subtype. Influenza A group 1 HA, influenza A group 2 HA, and influenza B viruses are indicated by brackets. HA subtypes that are recognized by a given MAb are indicated by colored stars. 6F12 only binds HAs within group 1 and is shown in green. KB2 binds H1, H5 and H6 and is shown in red. 2B06 binds H1, H5, H3, and H7 and is shown in orange. 2G02, FI6, and CR9114 MAbs are highly cross-reactive, and their breadth is illustrated by blue, purple, or magenta, respectively. The scale bar represents a 10% difference in amino acid sequence.