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. 2021 Oct 25;2021(10):CD012612. doi: 10.1002/14651858.CD012612.pub2

Hsieh 2012.

Study characteristics
Methods Randomised block‐controlled trial
Randomised using random numbers; stratification based on lesion side and motor deficit level
Robot therapy (RT) was Bi‐Manu‐Track (allows forearm supination/pronation and wrist flexion/extension) with duration control of 3 groups (90–105 minutes)
Repetitions were high or low intensity with high having twice the number of repetitions per unit time than lower
Before RT, 5 minutes of mobilisation and afterwards 15–20 minutes of functional activities practice
Control group had intensive standard therapy
For this Cochrane Review, we only compared the 2 RT groups
Participants 54 participants in 3 study groups
High RT: n = 18; mean age 56.5 (SD 10) years; 11 males; 28.7 (SD 13.7) months between stroke and randomisation
Low RT: n = 18; mean age 52.2 (SD 12) years; 13 males; 23.3 (SD 15.4) months between stroke and randomisation
No differences between these or other characteristics
Participants were all > 6 months poststroke
Interventions Intervention was RT
All participants received a duration‐matched intervention for 90–105 minutes of therapy per day, for 5 days per week for 4 weeks
Higher‐intensity RT: 600–800 repetitions of modes 1 and 2 for 15–20 minutes and 150–200 reps of mode 3 for 3–5 minutes
Lower‐intensity RT: received half the number of repetitions as the higher‐intensity group
Outcomes Upper extremity items of the FMA
Medical Research Council Scale (muscle power scale 0–5)
Motor Activity Log (amount of use and quality of movement)
4 physical domains on the SIS (strength, ADLs, mobility, and hand function)
Pain (scale 0–10)
Fatigue (scale 0–10)
All measures were administered at baseline and immediately after intervention. The primary outcome was also administered 2 weeks after the treatment began
Notes Authors provided mean and SDs for the post‐treatment Motor Activity Log (amount of use) and SIS hand function, as these were presented as change scores in the paper
Conflict of interest: none
Funding:  supported in part by the National Health Research Institutes (NHRI‐EX101‐9920PI and NHRI‐EX101‐10010PI), the National Science Council (NSC‐100‐2314‐B‐002‐008‐MY3 and NSC 99‐2314‐B‐182‐014‐MY3), and the Healthy Ageing Research Center at Chang Gung University (EMRPD1A0891) in Taiwan