TABLE 1. Variables in the Patient Dataset.

Variable name	All sample	Moderate risk	Severe risk	≈ p-value (chi squared test)
Boolean variables
Sex	207 men	145 men	62 men	0.5702
	94 women	69 women	25 women
Symptoms	% presence (no.)
Fever	93 (280)	92.5 (198)	94.3 (82)	0.6382
Cough	66.8 (201)	68.7 (147)	62.1 (54)	0.2804
Dyspnea	55.1 (166)	47.7 (102)	73.6 (64)	5E-04
Respiratory Failure (IR)	13 (39)	8.9 (19)	23 (20)	0.002
Myalgias	9.3 (28)	9.3 (20)	9.2 (8)	1
Other	9.6 (29)	9.8 (21)	9.2 (8)	1
Syncope	4.3 (13)	5.1 (11)	2.3 (2)	0.3598
Asthenia	12.3 (37)	11.7 (25)	13.8 (12)	0.6932
Vomiting.Nausea	5 (15)	4.2 (9)	6.9 (6)	0.3963
Diarrhea	10.3 (31)	10.7 (23)	9.2 (8)	0.8356
Headache	3 (9)	3.3 (7)	2.3 (2)	0.7346
Pharyngeal.pain	3 (9)	3.7 (8)	1.1 (1)	0.2894
Comorbidities	% presence (no.)
Pneumo.asthma	4.7 (14)	5.1 (11)	3.4 (3)	0.5852
Pneumo.BPCO	5.3 (16)	4.2 (9)	8 (7)	0.2659
Neoplasia (last 5 years)	10.6 (32)	7.9 (17)	17.2 (15)	0.0235
Smoke	5.3 (16)	5.6 (12)	4.6 (4)	0.7836
Arterial.hypertension	29.9 (90)	26.2 (56)	39.1 (34)	0.039
Cardiovascular pathologies	16.6 (50)	11.7 (25)	28.7 (25)	0.001
Diabetes	15.9 (48)	12.1 (26)	25.3 (22)	0.0045
Obesity	6 (18)	5.6 (12)	6.9 (6)	0.7976
Celebral Stroke	4 (12)	3.7 (8)	4.6 (4)	0.7536
Integer- and real-valued variables
	All sample	Moderate risk	Severe risk	≈ p-value (one-sided Wilcoxon signed-rank test)
Counts	mean ± s.e. [range]
No.Symptoms	3 ± 0.09 [0, 7]	3 ± 0.1 [0, 7]	3 ± 0.17 [0, 6]	class 0< class 1, 0.0224
No.Comorbidities	1 ± 0.09 [0, 6]	1 ± 0.1 [0, 5]	1 ± 0.19 [0, 6]	class 0< class 1, 4E-04
Symptoms.No.days	7 ± 0.29 [1, 30]	7 ± 0.36 [1, 30]	7 ± 0.51 [1, 20]	class 0<class 1, 0.4752
Age	62 ± 1.15 [23, 95]	58 ± 1.34[23, 92]	67 ± 1.88 [23, 95]	class 0< class 1, 0
Radiological variables	mean ± s.e. [range]
usa.radio.score.MAX1	3 ± 0.14 [0, 6]	3 ± 0.16 [0, 6]	4 ± 0.24 [0, 6]	class 0< class 1, 1E-04
radio.SCORE1	9 ± 0.26 [0, 18]	8 ± 0.31 [0, 16]	10 ± 0.46 [0, 18]	class 0< class 1, 0
GEO.extent.score2	4.22 ± 0.07 [1.45, 6.30]	4.01 ± 0.08 [1.45, 6.22]	4.74 ± 0.1 [1.73, 6.30]	class 0< class 1, 0
OPC.extent.score2	3.1 ± 0.06 [1.17, 4.85]	2.92 ± 0.07 [1.17, 4.85]	3.55 ± 0.1 [1.24, 4.85]	class 0< class 1, 0
Saturation values	mean ± s.e. [range]
PaO2.PF	310 ± 9.18 [40, 733]	333 ± 9.57 [61, 733]	231 ± 16.59 [40, 567]	class 0< class 1, 0
SpO2.in.FA	93 ± 0.46 [65, 100]	95 ± 0.37 [82, 100]	88 ± 1.07 [65, 98]	class 0< class 1, 0
Laboratory variables	mean ± s.e. [range]
ALT	35 ± 3.51 [4, 486]	34 ± 3.69 [4, 378]	42.5 ± 7.96 [9, 486]	class 0< class 1, 0.0448
Platelets	199 ± 6.6 [7, 792]	196.5 ± 8 [7, 792]	205 ± 11.69 [34, 513]	class 0< class 1, 0.4784
White.blood.cells	8.45 ± 0.71 [1.65, 179.67]	7.54 ± 0.54 [2.3, 109.77]	10.66 ± 2.05 [1.65, 179.67]	class 0< class 1, 0.0041
Red.blood.cells	4.64 ± 0.04 [2.56, 7.65]	4.68 ± 0.04[2.56, 7.65]	4.53 ± 0.07 [2.86, 6.43]	class 0> class 1, 0.0266
Lymphocyte	2.49 ± 0.76 [0.11, 172.48]	2.22 ± 0.65 [0.25, 98]	3.12 ± 2.04 [0.11, 172.48]	class 0> class 1, 1E-04
perc.Lymphocyte	17.94 ± 0.72 [0.6, 96]	19.7 ± 0.84 [3.3, 85.4]	13.72 ± 1.29 [0.6, 96]	class 0> class 1, 0
CRP3	8.92 ± 0.46 [0.05, 34.7]	7.01 ± 0.46 [0.05, 27.85]	13.66 ± 0.96 [0.77, 34.7]	class 0< class 1, 0
Haemoglobin	13.49± 0.11 [7.16, 19.1]	13.63 ± 0.12 [7.16, 19.1]	13.14 ± 0.21 [8.6, 17.7]	class 0> class 1, 0.0124
Haematocrit	38.88 ± 0.29 [21, 64]	39.18 ± 0.34 [21, 64]	38.12 ± 0.54 [25.3, 51.1]	class 0> class 1, 0.0336

¹Radiological value automatically computed by human,

²Radiological value automatically computed by CovidNet,

³CRP=C-Reactive Protein.