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. 2021 Oct 8;118(42):e2103526118. doi: 10.1073/pnas.2103526118

Fig. 2.

Fig. 2.

TssS inhibits the host innate immune response. (A) RNA-seq results of different ISGs of mouse PMs infected with Yptb WT or ΔtssS. RPKM: reads per kilobase of exon model per million mapped reads. (B) qRT-PCR analysis of the gene expression in PMs infected with Yptb WT, ΔtssS, or ΔtssS(tssS). (C) Immunoblot analysis of the protein expression in PMs infected with Yptb WT, ΔtssS, or ΔtssS(tssS). (D) qRT-PCR analysis of gene expression in the cecum of C57BL/6 mice mock infected or infected intragastrically with Yptb WT or ΔtssS for 72 h. (E) qRT-PCR analysis of gene expression in PMs infected with heat-inactivated strains. Data in B, D, and E were normalized to mock-infected control (Mock, set as 1), and Gapdh was used as the housekeeping gene. Error bars represent ± SEM; *P < 0.05; **P < 0.01; ***P < 0.001; NS, not significant.