Figure 6.

Simulated voxel-wise (gray) and averaged (red) spectral profiles within the localization volume in the phantom study are shown in (a) magnitude and (b) phase. To account for the phase variations due to B1+ and B0 fields, each voxel-wise profile has been phase corrected by its on-resonance echo for better visualization. The acquired spectra (real part) of the central voxel in the excitation ROI are shown in (c) and can be phase-corrected by using water spectra as reference (blue) or by adding a predicted quadratic phase term (red) in post-processing, as shown in (d). The spectra from semi-LASER were shown in (e), which was acquired with TR/TE = 2500/76 ms, whereas spectra acquired with proposed method used TR/TE = 2000/31 ms. Both spectra were acquired with the minimized echo time of the sequence and not optimized with respect to the J-modulation of citrate.