Illustration of proposed immune cell and molecule interactions that contribute to resolution of inflammation during bone healing. DHA: docosahexaenoic acid, EPA: eicosapentaenoic acid, RvD1: resolving D1, PGJ2: prostaglandin J2, MaR1: maresin 1, RvE1: resolvin E1, LXA4: lipoxin A4, TGF-β: transforming growth factor-beta, IL-4: interleukin-4, IL-10: interleukin-10, IL-13: interleukin-13, Breg: Regulatory B cell, Treg: regulatoru T cell, Th1: T helper 1. Th2: T helper 2.