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. 2021 Oct 9;3(4):fcab238. doi: 10.1093/braincomms/fcab238

Figure 8.

Figure 8

Treatment with low dose BTZ modulated relative expression of Ikba and Nfkb into an anti-inflammatory direction in the sciatic nerve. Results of qPCR of Ikba, shown in A, and Nfkb, shown in B, after treatment of EAN rats with 5% DMSO, 0.1 and 0.05 mg/kg BTZ. Data were normalized using the reference genes Actb and Gapdh and are presented relative to the control group 5% DMSO. Treatment with 0.05 mg/kg BTZ significantly increased the relative expression of Ikba (P-value = 0.0455) and reduced Nfkb (P-value = 0.0071) expression level (one-way ANOVA followed by Dunnett’s multiple comparison test). The experiment was performed twice. The figure shows the results of one representative experiment. Statistical analysis was performed with a technical N of 8, therefore each data point represents a technical replicate.