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Recovery and matrix effect in mouse plasma and liver homogenates from four independent experiments.
| Matrix | Nominal Concentrations (ng/mL) | Recovery (mean ± SD, (%CV) %) | Matrix Effect (mean ± SD, (%CV) %) |
|---|---|---|---|
| Plasma | 2 | 106 ± 7 (6%) | 100 ± 10 (13%) |
| 25 | 104 ± 8 (8%) | 96 ± 6 (6%) | |
| 200 | 98 ± 3 (3%) | 100 ± 4 (4%) | |
|
| |||
| Liver | 2 | 96 ± 7 (7%) | 110 ± 10 (11%) |
| 25 | 100 ± 6 (6%) | 95 ± 7 (7%) | |
| 200 | 102 ± 2 (2%) | 100 ± 10 (11%) | |
