Figure 1.

In meso crystallization and SSX analysis of membrane proteins in CrystalDirect plates

On the left is a CrystalDirect (CD) plate with LCP crystallization experiments (inset). Once LCP crystals have grown, two different workflows for structural analysis can be applied under the same crystallization conditions. Room-temperature in situ X-ray diffraction data can be collected directly from the CrystalDirect plate (middle top). For cryogenic structures (middle bottom), a workflow including automated laser-based harvesting and cryo-cooling can be utilized. Room-temperature and cryogenic structures of ADIPOR2 (right, top and bottom, respectively) obtained with these approaches are shown.