Fig. 1.

Structural representation of the FP-2 protein. A) and B) Subsites are illustrated as a pale green surface. The ART linked mutations are in firebrick, and the rest of the mutations are in grey spheres. The three catalytic residues (C285, H417, N447) are also labelled. C) and D) Identified pockets are shown in surface presentation. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)