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. 2021 Oct 25;3(1):e62–e71. doi: 10.1016/S2666-5247(21)00240-8

Table 4.

Clinical factors associated with unfavourable outcomes among patients with COVID-19

Patients with unfavourable COVID-19 outcomes*(n=73) Patients discharged in good condition (n=524) Crude OR (95% CI) Adjusted OR (95% CI) p value
Age categories*
0–20 years 2 (3%) 21 (4%) Ref Ref ..
21–40 years 32 (44%) 323 (62%) 1·0 (0·2–4·6) 1·8 (0·2–14·0) 0·58
41–60 years 18 (25%) 145 (28%) 1·3 (0·3–6·0) 1·9 (0·2–15·8) 0·53
>60 years 19 (26%) 27 (5%) 7·4 (1·5–35·3) 8·7 (1·0–75·5) 0·049
Sex
Male 59 (81%) 443 (85%) Ref Ref ..
Female 14 (19%) 81 (15%) 1·3 (0·7–2·4) 0·9 (0·4–1·9) 0·82
Current malaria infection
Negative 65 (89%) 462 (88%) Ref Ref ..
Positive 8 (11%) 62 (12%) 0·9 (0·4–2·0) 0·8 (0·3–2·0) 0·66
Previous malaria exposure
Moderate 53 (73%) 365 (70%) Ref Ref ..
Low 10 (14%) 43 (8%) 1·6 (0·8–3·4) 1·1 (0·5–2·5) 0·84
High 6 (8%) 50 (10%) 0·8 (0·3–2·0) 1·0 (0·4–2·6) >0·99
Diabetes
No 57 (78%) 488 (93%) Ref Ref ..
Yes 16 (22%) 33 (6%) 4·2 (2·2–8·0) 2·1 (0·9–5·0) 0·077
Heart disease
No 64 (88%) 501 (96%) Ref Ref ..
Yes 7 (10%) 16 (3%) 0·3 (0·1–0·7) 0·5 (0·2–1·5) 0·22

OR=odds ratio. Ref=reference.

*

Defined as death, discharge with sequelae, or requiring intensive care.