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. Author manuscript; available in PMC: 2022 Nov 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2021 Sep 30;431:115730. doi: 10.1016/j.taap.2021.115730

Fig. 1.

Fig. 1.

Characterization of body weight and serum lipid levels in healthy and MetS mouse models following 14 weeks on either a healthy or high-fat western diet (HFWD). Thirty minutes prior to oropharyngeal aspiration of pharmaceutical grade sterile water (control) or AgNPs (50 μg) in sterile water, mice were i.p. injected with 1 μg of 14-HDHA, 17-HDHA, or 18-HEPE or vehicle (250 μl of sterile saline). Healthy and MetS mice without or with lipid interventions were characterized by examination of (A) body weight (BW), (B) serum total cholesterol (TC), (C) serum high-density lipoprotein (HDL), (D) serum low-density lipoprotein (LDL), and (E) serum triacylglycerides (TG) levels. Values are expressed as mean ± SEM (n = 6–8/group). # denotes significant differences between healthy and MetS models receiving similar treatment and exposure, (p < 0.05).