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. 2021 Oct 25;11:21022. doi: 10.1038/s41598-021-00497-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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S. aureus after 12, 24, 48 times culture with sublethal concentrations of Cefuroxime and Pln149 using a 0.5 McFarland inoculum that were characterized by 100ug Cefuroxime and Pln149 disk diffusion test (A original strain; B S. aureus after 12 times culture; C S. aureus after 24 times culture; D S. aureus after 48 times culture; 1: Pln149 groups; 2: Cefuroxime groups; c: control groups).