Table 3.
Multivariate modeling of regional volume by cumulative seizure burden
| Regional Volume Name | Uncorrected, t Value |
Uncorrected, p Value |
Corrected, t Value |
Corrected, p Value |
|---|---|---|---|---|
| CSF | −2.51 | 0.01 | 3.52 | <0.01 |
| Gray Matter | −2.89 | <0.01 | 0.55 | 0.59 |
| White Matter | −6.34 | <0.01 | −2.10 | 0.03 |
| Deep Nuclear Gray Matter | −3.91 | <0.01 | −0.93 | 0.38 |
| Cerebellum | −3.41 | <0.01 | −0.49 | 0.63 |
Values provide for volumes uncorrected and corrected for total intracranial volume. All models adjusted for gestational age, antenatal steroids, WMI severity, IVH severity, presence of CH, necrotizing enterocolitis, culture positive sepsis, BPD, and postnatal steroid exposure.