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. 2021 Sep 27;108(10):1866–1879. doi: 10.1016/j.ajhg.2021.08.014

Figure 2.

Figure 2

Prioritizing complex disease-relevant environmental perturbations via heritability enrichment analysis

Heritability enrichment results for each complex trait. Each point represents a perturbation-cell-line combination that passes the FDR < 10% cut-off. The y axis represents the −log10(p value) of heritability enrichment, the x axis indicates perturbation, the color of the point indicates cell line, and the shading color within each panel indicates the perturbation category from Figure 1A. Numerical results are reported in Data S9.