Table 2.

Gene-based rare variant associations with white blood cell counts in TOPMed

Trait	Gene	Number of variants	Discovery p value	INTERVAL p value	UKBiobank p value
NEU	MARCKSL1	11	2.98 × 10−7	0.5576	0.1008
LYM	CNKSR2	13	2.46 × 10−6	0.8067	0.8079
MON	TET2	72	6.21 × 10−9	0.6984	0.6091
MON	FLT3	65	8.96 × 10−7	0.0003	2.42 × 10−18