Table 3. Reliability Between Parameters Extracted from Semi-Automatic Segmentation and Fully Automatic Segmentation.

		All (n = 89)	Subgroup (n = 55)
Volume		0.971 (0.956–0.981)	0.982 (0.969–0.990)
Diameter		0.932 (0.896–0.955)	0.958 (0.928–0.976)
First-order
	Mean	0.967 (0.949–0.978)	0.958 (0.927–0.975)
	Variance	0.744 (0.611–0.832)	0.786 (0.631–0.875)
	Energy	0.899 (0.846–0.934)	0.904 (0.835–0.944)
	Entropy	0.841 (0.758–0.895)	0.871 (0.779–0.925)
	Skewness	0.407 (0.095–0.611)	0.446 (0.049–0.677)
	Kurtosis	0.455 (0.171–0.641)	0.207 (−0.345–0.534)
	Uniformity	0.827 (0.736–0.886)	0.874 (0.786–0.927)
Second-order
	GLCM IDM	0.980 (0.966–0.987)	0.987 (0.977–0.997)
	GLCM contrast	0.967 (0.930–0.982)	0.966 (0.931–0.982)
	GLCM correlation	0.706 (0.552–0.807)	0.756 (0.590–0.859)
	GLCM sum average	0.715 (0.567–0.812)	0.529 (0.204–0.723)
	GLCM diff average	0.978 (0.961–0.987)	0.983 (0.969–0.991)
	GLCM sum entropy	0.828 (0.739–0.887)	0.864 (0.767–0.921)
	GLCM diff entropy	0.960 (0.909–0.979)	0.968 (0.927–0.984)
Shape
	Compactness1	0.293 (−0.080–0.537)	0.520 (0.192–0.717)
	Compactness2	0.215 (−0.201–0.486)	0.523 (0.197–0.718)
	Elongation	0.562 (0.332–0.713)	0.775 (0.615–0.869)
	Flatness	0.638 (0.449–0.762)	0.792 (0.614–0.884)
	Sphericity	0.314 (−0.047–0.550)	0.515 (0.185–0.714)

Data are intraclass correlation coefficient values with 95% confidence interval in parentheses. Subgroup analysis was performed after excluding 34 tumors with ill-defined margins.

diff = difference, GLCM = Gray-Level Co-occurrence Matrix, IDM = inverse difference moment