TABLE 5.
Relationships between heat shock protein expressions and copy number variations in pan-cancer.
| Gene name | CNVCat | N | Expression median value | p Value | CancerType |
|---|---|---|---|---|---|
| HSPA2 | DEL | 62 | 10.303 (9.167–11.658) | 0.011 | BRCA |
| GAIN | 29 | 12.051 (9.649–12.666) | |||
| No Change | 999 | 10.844 (9.735–12.004) | |||
| DEL | 3 | 9.011 (8.298–9.706) | 0.043 | GBM | |
| GAIN | 2 | 12.016 (11.549–12.483) | |||
| No Change | 159 | 11.152 (10.204–11.958) | |||
| DEL | 9 | 11.291 (9.502–12.274) | 0.024 | HNSC | |
| GAIN | 25 | 13.069 (11.437–13.797) | |||
| No Change | 462 | 12.096 (10.908–13.071) | |||
| DEL | 43 | 11.47 (10.509–12.65) | 0.003 | LGG | |
| No Change | 485 | 12.356 (11.421–13.173) | |||
| DEL | 23 | 8.607 (7.803–9.212) | 0.006 | LUSC | |
| GAIN | 13 | 10.18 (8.972–11.133) | |||
| No Change | 464 | 9.377 (8.373–10.489) | |||
| DEL | 60 | 9.21 (8.658–10.157) | <0.001 | OV | |
| GAIN | 23 | 10.852 (9.678–11.543) | |||
| No Change | 294 | 10.212 (9.423–10.997) | |||
| DEL | 7 | 9.264 (8.243–9.698) | 0.001 | UCEC | |
| GAIN | 16 | 10.572 (10.139–11.177) | |||
| No Change | 517 | 9.557 (8.748–10.514) | |||
| HSPD1 | DEL | 19 | 14.242 (13.87–14.568) | <0.001 | BRCA |
| GAIN | 60 | 15.065 (14.404–15.626) | |||
| No Change | 1,011 | 14.287 (13.784–14.794) | |||
| DEL | 8 | 13.737 (13.554–13.977) | <0.001 | CESC | |
| GAIN | 21 | 14.891 (14.629–15.34) | |||
| No Change | 265 | 13.988 (13.442–14.525) | |||
| DEL | 12 | 14.339 (13.909–14.924) | 0.013 | ESCA | |
| GAIN | 10 | 15.273 (15.023–15.438) | |||
| No Change | 139 | 14.785 (14.316–15.189) | |||
| DEL | 27 | 13.661 (13.244–14.158) | <0.001 | HNSC | |
| GAIN | 26 | 14.896 (14.208–15.524) | |||
| No Change | 443 | 14.036 (13.506–14.512) | |||
| DEL | 11 | 13.422 (12.664–13.688) | 0.002 | KIRC | |
| GAIN | 7 | 14.302 (14.146–14.692) | |||
| No Change | 512 | 14.146 (13.715–14.602) | |||
| DEL | 1 | 13.507 (13.507–13.507) | 0.001 | KIRP | |
| GAIN | 7 | 15.782 (15.079–16.231) | |||
| No Change | 279 | 14.106 (13.647–14.754) | |||
| DEL | 3 | 14.062 (13.968–14.761) | 0.029 | LIHC | |
| GAIN | 14 | 15.097 (14.695–15.415) | |||
| No Change | 355 | 14.489 (13.979–14.991) | |||
| DEL | 25 | 13.866 (13.364–14.265) | <0.001 | LUSC | |
| GAIN | 34 | 15.343 (15.184–15.612) | |||
| No Change | 441 | 14.33 (13.791–14.855) | |||
| DEL | 27 | 13.798 (13.424–14.083) | <0.001 | OV | |
| GAIN | 68 | 14.658 (14.153–15.103) | |||
| No Change | 282 | 14.205 (13.669–14.636) | |||
| GAIN | 6 | 14.156 (13.693–14.566) | 0.032 | PAAD | |
| No Change | 171 | 13.399 (12.9–13.861) | |||
| DEL | 4 | 14.354 (14.184–14.737) | 0.01 | PRAD | |
| GAIN | 6 | 15.644 (15.17–15.92) | |||
| No Change | 486 | 14.09 (13.666–14.491) | |||
| DEL | 7 | 13.876 (13.827–14.053) | 0.005 | SKCM | |
| GAIN | 8 | 15.292 (14.784–15.408) | |||
| No Change | 455 | 14.426 (13.823–14.92) | |||
| DEL | 11 | 14.022 (13.528–14.122) | 0.007 | STAD | |
| GAIN | 14 | 15.382 (14.203–15.79) | |||
| No Change | 348 | 14.44 (13.778–15.003) | |||
| DEL | 6 | 14.111 (13.133–14.18) | 0.003 | UCEC | |
| GAIN | 14 | 14.22 (13.973–15.407) | |||
| No Change | 520 | 13.136 (12.395–14.042) |
N represented sample size.