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. 2021 Oct 12;12:758080. doi: 10.3389/fphar.2021.758080

FIGURE 2.

FIGURE 2

Empagliflozin (EMP) improved cardiac function after cardiac arrest in rats. (A) Effect of EMP on heart rate within 1 h after return of spontaneous circulation (ROSC) (n = 7–10). (B) Effect of EMP on mean artery pressure (MAP) within 1 h after ROSC (n = 7–10). (C) EMP increased left ventricular ejection fraction at 24 h after ROSC (n = 6). (D) EMP increased cardiac output at 24 h after ROSC (n = 6). (E) EMP improved survival of the rats after cardiac arrest within 24 h (n = 10). Data are presented as mean ± SD, *p < 0.05, **p < 0.01.