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. 2021 Oct 12;12:754710. doi: 10.3389/fimmu.2021.754710

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Copyright © 2021 Crowley, Osei-Owusu, Dekkers, Gao, Wuhrer, Magnani, Reimann, Pincus, Vidarsson and Ackerman

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Summary of receptor affinity differences. Statistical significance of differences in affinity associated with variable glycosylation. Glycan modifications are tabulated by row and receptors by column, for each of the two independent experimental runs. Confidence in differences is indicated in color. Crosshatches indicate missing data. The effect of varying (+ versus -) sialic acid, bisecting GlcNAc, and fucose were evaluated by unpaired t test, and for galactose [+G, unmodified (base), and -G] with an ordinary one-way ANOVA corrected for multiple comparisons.