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. 2021 Oct 12;12:754710. doi: 10.3389/fimmu.2021.754710

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Copyright © 2021 Crowley, Osei-Owusu, Dekkers, Gao, Wuhrer, Magnani, Reimann, Pincus, Vidarsson and Ackerman

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Similar FcγR binding glycopreferences are observed for RM serum IgG. (A) Correlations of receptor binding signal in multiplex assay and glycan species prevalence in rhesus macaque serum IgG for each allotypic variant of RM FcγRIIa and FcγRIIIa. Unadjusted Spearman correlation coefficient (R_S) strength and direction are indicated in color, and confidence (p value) in size. (B) Exemplary scatter plots of relatively stronger correlative relationships between relative galactose and fucose content (% peak area) in relation to FcγR binding median fluorescent intensity (MFI). Correlation coefficients and exact p values are indicated in inset.