Table 3.
Substance Vaped in Relation to Qualitative Severity and Common Imaging Findings
| Demographic or CT Variable | Substance Vaped (N = 160) |
P Valuea | ||
|---|---|---|---|---|
| THC and Nicotine (n = 68) | THC Only (n = 77) | Nicotine Only (n = 15) | ||
| Age, y | 25.5 ± 10.3 | 29.4 ± 10.9 | 33.6 ± 13.9 | NS |
| BMI, kg/m2 | 26.6 ± 6.9 | 26.1 ± 7.1 | 27.1 ± 7 | NS |
| Symptom duration | 11.4 ± 22.9 | 8.5 ± 8.9 | 17.5 ± 28.5 | NS |
| Qualitative severity (CT scan) | ||||
| Mild | 5 (7.4) | 17 (22.0) | 3 (20.0) | NS |
| Moderate | 41b(60.3) | 28 (36.4) | 6 (40.0) | .031 |
| Severe | 22 (32.3) | 32 (41.6) | 6 (40.0) | NS |
| Parenchymal attenuation | ||||
| GGO only | 35 (51.5) | 42 (54.5) | 5 (33.3) | NS |
| GGO > consolidation | 14 (20.6) | 19 (24.7) | 7 (46.7) | NS |
| Mixed | 16 (23.5) | 12 (15.6) | 2 (13.3) | NS |
| Consolidation > GGO | 3 (4.4) | 4 (5.2) | 1 (6.7) | NS |
| Parenchymal sparring | ||||
| Subpleural | 51 (75) | 63 (81.8) | 11 (73.3) | NS |
| Lobular | 41 (60.3) | 45 (58.4) | 9 (60.0) | NS |
| Peribronchovascular | 28 (41.2) | 31 (40.3) | 4 (26.7) | NS |
| Centrilobular nodules | 31 (45.6) | 24 (31.2) | 4 (26.7) | NS |
| Septal thickening | ||||
| Interlobular | 39 (57.4) | 34 (44.2) | 8 (53.3) | NS |
| Crazy paving | 16 (23.5) | 10 (13.0) | 4 (26.7) | NS |
| Lymphadenopathy | 43 (63.2) | 45 (58.4) | 12 (80) | NS |
| Pleural effusions | 13 (19.1) | 18 (23.4) | 4 (26.7) | NS |
Values are No. (%), mean ± SD, or as otherwise indicated. Bold denotes statistical significance. GGO = ground-glass opacity; NS = nonsignificant; THC = tetrahydrocannabinol.
a
After Bonferroni correction.
b
Variable with significant difference after Bonferroni correction.