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. 2021 Oct 12;13:743573. doi: 10.3389/fnagi.2021.743573

Table 3.

MicroRNAs and their key target genes in the microglia.

miRNA Target Gene Gene function References
miR-124 C/EBP-α Microglial Polarization to M2 Ponomarev et al., 2011
miR-155 C-MAf, CCM1, NOX2, NOX4 Microglial polarization to M2, microglial activation and increased count Guo et al., 2019
miR-9 NF-kB Microglial activation Yao et al., 2014
miR-204 SIRT1 Repression of microglial activation Li L. et al., 2015
miR-125b NF-kB Contributing in increased TNF-α release Parisi et al., 2013
miR-34a TREM2 Aβ42 aggregation and accumulation and microglial activation Alexandrov et al., 2013